Obesity carries significant health risks. Although bariatric surgery is an effective treatment for severe obesity, its long-term effects on diet, appetite and physical activity remain unclear[1-3].
This prospective study followed 57 adults over 36 months following Roux-en-Y gastric bypass (RYGB, n=7), sleeve gastrectomy (SG, n=21), laparoscopic adjustable gastric banding (LAGB, n=11) and dietary intervention (Diet, n=18). Dietary intake was recorded using 3-day food diaries, appetite measured via visual analogue scales and physical activity quantified by validated questionnaires covering light (<3.0 METs), moderate (3.0–6.0 METs), and vigorous (>6.0 METs) exercise. Within-group changes were analysed using Wilcoxon signed-rank tests.
At 36 months, SG and RYGB groups showed sustained weight loss (-30.6 kg and -28.5 kg, p<0.02), respectively, whereas LAGB induced early weight loss (-12.6 kg at 6 months, p<0.01) followed by partial regain. Diet lost weight initially (-2.7 kg at 12 months, p<0.01) returning to baseline by 24 months.
Energy intake decreased sharply after surgery in SG (-68%) and RYGB (-64%) at 1 month (p<0.01), with sustained reductions (36-40%) at 36 months. However, fat intake declined significantly in SG (35% to 28%) and RYGB (34.5% to 25.0%), while protein intake increased in both (up to 25.5% and 32.0%, respectively) for 3 months only, with no sustained difference after 12 months. RYGB showed reduced carbohydrate intake and increased calcium intake (up to 1428.0 mg) at 3 years. LAGB did not change macronutrient intake beyond 12 months.
Physical activity increased significantly in RYGB (light: +165min/day; moderate: +112.5min/day at 36 months) and up to 24 months in SG. Appetite suppression persisted up to 24 months after RYGB and 36 months after SG (p<0.01).
SG and RYGB improved weight, intake, and appetite, with RYGB showing the greatest physical activity gain. LAGB showed less durable effects, highlighting the need for ongoing nutritional and behavioural support.