Tuesday, 21st October ESA-SRB-ANZOS 2025 in conjunction with ENSA

Experts will explore the link between obesity and cardiovascular disease and discuss strategies for effective obesity management that focuses on comprehensive health outcomes beyond just weight loss. 

Speakers:

Dr Mark Mellor - General Practitioner
A/Prof Samantha Hocking - Endocrinologist
A/Prof Melissa Leung - Cardiologist

Breakfast will be provided for this session.

• The tubulin glutamylase TTLL1 is required for spermatid differentiation and male fertility in mice - Tao Tang

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• Novel endocrine links between reproduction and metabolism in females - Kelly Walton

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• Aldosterone, Mineralocorticoid Receptor and Cardiometabolic Disease - Gail Adler

• Long life and fertility: ovarian metabolism as a target for reproductive ageing - Lindsay Wu

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• Harnessing the power of hepatokines for therapeutic gain - Matthew Watt

• Fractures, Frameworks, Frontiers - Christian Girgis

9:50am-10:00am  ESA ECR Update - Amy Dwyer & Jillian Tay

ECR NETWORKING HUB SPEAKERS

ESA: Dr Emily Meyer & Dr Annabelle Warren
SRB: Dr Nicole McPherson
ANZOS: Prof Melanie Cree

• Lost in the System – Pacific children and young people in Aotearoa/New Zealand; disproportionately affected but poorly supported - Collin Tukuitonga
• Aboriginal Engagement Lead, Health Consumers’ Council presentation - Mel Robinson
• Aboriginal Engagement Lead, Health Consumers’ Council presentation - Tania Harris
• “Lost in the System”: Psychological Insights from Lived Experience of Obesity and the Clinical Power of Consent - Theresa A Thompson

• Mapping interactions between dietary macronutrients and sex across the lifecourse - Amanda Brandon
• Does salt matter in metabolism? - Yanchuan Shi
• YAP/TAZ integrate adipose tissue remodeling with endocrine regulation of energy homeostasis - Jae Myoung Suh
• Mitochondrial lipids permit hepatocyte mitophagy and suppress MASH - Jacob Qi

• Kingdom of reproductive life; core sperm proteome - David Skerrett-Byrne

• Management of Adults with Differentiated Thyroid Cancer – Updates from the New ATA Guidelines 2025 - Bruce Robinson
• Radiofrequency Ablation in the Management of Thyroid Disease - Catherine Sinclair
• Implementing molecular imaging in functional endocrine neoplasia of the head and neck. - James McNeil
• Cancer Immunotherapy-related Endocrinopathies - Melissa Lechner

• Peri-conceptional administration of viral mimetic poly I:C attenuates maternal immune and vascular parameters to impair placental and fetal development - Stacey J Savin
• Use of microchannels to add selective efficacy to a functionalised surface sperm selection device.   - Soraya Rasi Ghaemi
• Metformin and insulin exacerbate one-carbon metabolism deficits in pregnant growth restricted rats and impacts the placenta, fetal liver and pancreas - Dayna A Zimmerman
• Mapping the effects of chronic and acute activin A elevation on spermatogonial fate throughout life: implications for male fertility - Penny A. F. Whiley
• Defining the impact of endometriosis on the hormone responsiveness of human endometrial epithelia utilising endometrial epithelial organoids. - Jenna Douglas
• Preserving female fertility & offspring health after chemotherapy by inhibiting PUMA - Lauren R Alesi

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• AI for Everyday Research: Workflows That Save Time, Avoid Burnout, and Get Results - Andrew Stapleton

• Insights from the TOBOGM Randomised Controlled Trial: Time for a Lifecourse Approach to Gestational Diabetes Mellitus - David Simmons
• Perth Children's Hospital/Telethon Kids Institute Presentation - Tim Jones
• ANZ Joint Society Consensus on Genetic Testing for Monogenic Diabetes in Adults - Sunita De Sousa
• ORCHID Study - Emma Jamieson and Erica Spry

Considerations in pregnancy and adults

• Promise and Pragmatism: GPs’ Perspectives on GLP-1RAs for Obesity Management in NHS Primary Care - Cervantée Wild
• GLP-1RA Use for Obesity in Australia: Access, Affordability, and Support Gaps - Kate A McBride
• Association Between Dietary Patterns and Fat-Free Mass: A Systematic Review. - Mohammad Ariya
• Gender Inequality and Socio-Economic Disadvantages Associated with Obesity in Women Compared to Men: A Rapid Review of Observational Studies. - Nana Ama Asi Danso
• Diet quality and physical activity trajectories in pregnancy and associations with maternal characteristics - Miaobing Zheng
• Feeding the Feed: How Social Media Shapes the Digital Food Environment for Young People - Cervantée Wild
• Supporting weight focused discussions in primary care - Gemma Sharp
• Active school commuting and obesity prevention: a mixed-methods exploration with schoolchildren, parents, and other stakeholders in regional Australia - Ho Yeung Lam

• Maternal immune–vascular interactions shaping pregnancy outcomes - Alison Care
• Inhibin deficiency promotes adiposity in female mice - Adam Hagg
• Why Losing Weight Isn’t Enough: The Metabolic Truth About Male Fertility - Nicole McPherson
• Insights from 35 years of the Raine Study; Metabolic and Endocrine Influences on male infertility. - Roger Hart

• The vaginal microbiome as a modifier of pregnancy outcomes - David MacIntyre
• Counting your oocytes before they hatch: Early-life ovarian reserve does not influence lifetime fertility. - Nicholas J Anderson
• TGFB1 in the follicular fluid play a role in DNA methylation and subsequent embryonic development - Shunsuke Hara
• Fetal growth restriction induces dynamic, sex-specific changes to molecular signatures in the placenta-heart axis of the near-term sheep - Ashley S Meakin
• Engineering potent anti-Müllerian hormone analogues for in vivo testing in female domestic cats - William A Stocker
• The Impact of Oocyte-Secreted Factors on Ovarian Cancer Development - Sarah Sczelecki
• Elevating Ni-Vanuatu women’s voices through research on maternal health, nutrition, and adverse birth outcomes  - Georgia R Kafer

• Gaining Strength While Losing Weight: Functional Improvements During a Very Low Energy Diet - William Beningfield
• Co-development and implementation of a metabolic care pathway for adults living with cystic fibrosis at a tertiary adult centre - Shanal Kumar
• Evaluating whole fruit feijoa powder for type 2 diabetes risk prevention: the FERDINAND study - Ibrahim A Mohamed
• An observational study on the use of semaglutide in type 1 diabetes - Purnima (Darshi) Cheruvu
• Weight-independent benefits of semaglutide on histology and non-invasive tests in participants with biopsy-defined MASH: Post hoc analysis of the ESSENCE trial part 1 - Leon A Adams
• Evaluating the severity of obesity in adolescents presenting to an intensive behavioural weight management intervention - Natalie B Lister
• Characteristics of participants who regained weight after withdrawal of tirzepatide: A post hoc analysis of SURMOUNT-4 - Meg Henze
• From Crisis to Coordination: Impact of a Structured Obesity Treatment Program on Health Service Utilisation - Andrea Cawte

• ATF3-Regulated Eosinophils Drive Adipose Tissue Angiogenesis Via VEGFA Expression - Kate Quinlan
• Liraglutide ameliorates pathogenic changes in cardiac tissue proteins in female mice of reproductive age   - Matilda S G Longfield
• Cafeteria diet exposure, not propensity for weight gain, impacts composition of the gut microbiota of rats: a within laboratory meta-analysis of 12 studies - Margaret J Morris
• Comparing food addiction phenotypes in animal models of obesity and binge eating - Michael D Kendig
• Using genetics to understand drivers of obesity-linked endometrial cancer - Tracy A O'Mara
• Emerging Insights Into the Role of Brown Adipose Tissue in β-cell Function and Glucose Homeostasis - Chenxu Loki Yan
• An ad libitum-fed diet that matches the beneficial lifespan effects of caloric restriction but acts via opposite effects on the energy-splicing axis - Amanda Brandon

ECR NETWORKING HUB SPEAKERS

ESA: Dr Liz Johnstone
SRB: A/Prof Marloes Dekker Nitert
ANZOS: A/Prof Adam Rose

• Lipids, Lipoprotiens and Cardiovascular Health - Damon Bell
• Hypertension management in 2025 – what’s new? - Markus Schlaich
• Simplifying the diagnosis of primary aldosteronism - Elisabeth Ng
• Living with primary aldosteronism - Pamela Lincoln and Jun Yang

• Disrupting Polymerase Gamma Exonuclease in Adipose Tissue Protects Mice from Obesity and Related Complications - Moran Zhou
• Investigating the role of β-adrenergic signalling in triggering adipose-resident eosinophils to promote beiging - Tia J. Valentini
• Hybrid strains of mice with polygenic mitochondrial complex I insufficiency are obese and display features of cardiometabolic disease - Shannen Walker
• Development of adipose-derived eosinophil cell lines to uncover novel pro-beiging factors for treating obesity - Emmaline Lonergan

• Direct effects of survodutide on liver endpoints beyond weight loss: insights from a phase 2 trial of the glucagon receptor/glucagon-like peptide-1 receptor dual agonist survodutide in people with metabolic dysfunction-associated steatohepatitis and fibrosis - Nick Kontorinis
• Tirzepatide treatment and achieving weight reduction >5%, SBP reduction >5 mmHg and non-HDL cholesterol reduction >10%: A post hoc analysis from the SURMOUNT-1 3-year trial - Melissa Leung
• Incretin-based anti-obesity therapy: can we preserve muscle mass while losing fat? - Bu Yeap
• Incretin therapy and eating disorders: Friend or Foe? - Milan Piya
• Incretin-based anti-obesity therapy: will it make you blind? Finding facts and busting myths. - Kathryn Williams

5:30pm - Panel Discussion

• Bu Yeap
• Milan Piya
• Katheryn Williams

• Calcium shapes metabolic control of epigenetic reprogramming following fertilization to impact offspring health - Carmen Williams

Emerging Frontiers in Thyroid, Endocrine tumours, and Cancer Management

• Spatial profiling identifies novel biomarkers in aggressive pituitary neuroendocrine tumours - Lydia S Lamb
• Androgen receptor genomic structural rearrangements reshape the AR cistrome in castration-resistant prostate cancer - Mitchell Lawrence
• Androgen Receptor tumour suppressor activity is defined by GATA3 interaction and enhancer selectivity in ER⁺ breast cancers - Amy R Dwyer
• Application of a novel long-acting biotherapeutic targeting the growth hormone receptor in melanoma - Jo K Perry
• A Retrospective review of Radioactive Iodine Avidity in a Cohort of Patients with Oncoytic Thyroid Carcinoma; A Single Centre Review - Stephen Ludgate
• ANZ interdisciplinary survey of non-functioning pituitary adenoma management: areas of variability and common practice - Edward Mignone
• Observational study on hypothyroid patients with gastric disorders in treatment with liquid L-T4 therapy - Alessandro Antonelli
• Evolving morbidities and transition challenges for survivors of childhood posterior fossa tumours - Quynh-Nhu Nguyen

Childhood overweight and obesity

• Maternal protein intake during pregnancy and obesity risk in mothers and offspring: a prospective cohort study - Berit Lilienthal Heitmann
• Tarnishing the health halo: How warning labels and removal of nutrition content claims influence parental perceptions and purchases of commercial infant and toddler foods with added sugar. - Helen Dixon
• Replacing protein with carbohydrate or fat in infancy is associated with lower body weight in early childhood - Tinsae Shemelise Tesfaye
• Association of Health-Related Quality of Life and Weight Status throughout Childhood and Adolescence - Alison Hayes
• Countering sweet deception: the impact of added sugar warning labels on parental perceptions and purchasing preferences for commercial infant and toddler foods. - Helen Dixon
• Socioeconomic differences in the cost-effectiveness of a telephone-based intervention for obesity prevention in early childhood - Alison Hayes
• Postpartum health after gestational diabetes: insights from women on a behaviour change program using digital and coaching approaches - Jacqueline L. Walker
• Exploring and understanding weight stigma in First Nations peoples in the Northern Territory, Australia: a qualitative study - Seileshia Calma Goodrem and Anna J Wood

• Novel diagnostics and therapies to improve pregnancy outcomes - Fiona Brownfoot

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