Obesity remains a considerable burden to individuals, communities and the health system. Despite investment in a range of health initiatives over past decades, rates of obesity remain unacceptably high. The implementation of strategies to prevent obesity in children has been recommended in obesity strategies globally. Evidence supporting the effectiveness of these in reducing obesity child obesity prevalence, however, has been mixed. This presentation will describe the evolution of efforts to prevent obesity in Australia over the past 2 decades characterising different approaches and perspectives over this period. Despite significant advances in knowledge, technology, and perspectives on prevention, the translation of effective interventions into health policy and practices remains a persistent impediment to reducing population prevalence of obesity prevention programs. The novel application of scientific disciples including implementation science, methods and technologies will be discussed as potential means of improving the impact of investments in obesity prevention.